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(+)-trans-carveol dehydrogenase

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(+)-trans-carveol dehydrogenase
Identifiers
EC no.1.1.1.275
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, (+)-trans-carveol dehydrogenase (EC 1.1.1.275) is an enzyme that catalyzes the chemical reaction

 
 
 
H+
Reversible left-right reaction arrow with minor forward product(s) to top right and minor reverse substrate(s) from bottom right
 
H+
 
 

The two substrates of this enzyme are (+)-trans-carveol and oxidised nicotinamide adenine dinucleotide (NAD+). Its products are (+)-carvone, reduced NADH, and a proton.[1][2]

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-trans-carveol:NAD+ oxidoreductase. This enzyme is also called carveol dehydrogenase. This enzyme participates in monoterpenoid biosynthesis and the degradation of the terpenes limonene and pinene.

References

[edit]
  1. ^ Enzyme 1.1.1.275 at KEGG Pathway Database.
  2. ^ Bouwmeester HJ, Gershenzon J, Konings MC, Croteau R (1998). "Biosynthesis of the Monoterpenes Limonene and Carvone in the Fruit of Caraway : I. Demonstration of Enzyme Activities and Their Changes with Development". Plant Physiol. 117 (3): 901–12. doi:10.1104/pp.117.3.901. PMC 34944. PMID 9662532.