(+)-Sabinene 3-hydroxylase
| (+)-Sabinene 3-hydroxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.153 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
(+)-Sabinene 3-hydroxylase (EC 1.14.13.153) is an enzyme with systematic name (+)-sabinene,NADPH:oxygen oxidoreductase (3-hydroxylating). It catalyses the following chemical reaction
-sabinene.svg)
The four substrates of this enzyme are (+)-sabinene, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. It products are (+)-sabinol, oxidised NADP+, and water.[1]
The enzyme is a monooxygenase isolated from Salvia officinalis (common sage). Its active centre is a cytochrome P450.[2]
References
[edit]- ^ Enzyme 1.14.13.153 at KEGG Pathway Database.
- ^ Karp F, Harris JL, Croteau R (July 1987). "Metabolism of monoterpenes: demonstration of the hydroxylation of (+)-sabinene to (+)-cis-sabinol by an enzyme preparation from sage (Salvia officinalis) leaves". Archives of Biochemistry and Biophysics. 256 (1): 179–93. doi:10.1016/0003-9861(87)90436-x. PMID 3111374.
External links
[edit]- (+)-sabinene+3-hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
