Cellular & Molecular Immunology

T-cell receptor in complex with the MHC class II-peptide complex

Welcome to Cellular & Molecular Immunology

Featured

Short-, medium-, versus long-chain fatty acids: mechanisms of immunomodulation and disease pathogenesis

Chang H. Kim
Review ArticleOpen Access30 Apr 2026
Regulatory heme: a mitochondria-to-nucleus messenger of CD8⁺ T-cell exhaustion

Hao Song
Hao Shi
Hongbo Chi
Research Highlight22 Apr 2026
Defining the rules of engagement: B cells, antibodies and cancer control

Stephen L. Nutt
Julie Tellier
Jessica Da Gama Duarte
Review ArticleOpen Access06 May 2026
Inhibition of glycosphingolipid synthesis overcomes the steric hindrance of CD30 N-glycans to augment CD30-targeted immunotherapeutic efficacy

Yuting Pan
Yixin Chang
Weidong Han
Article27 Apr 2026

Current issue

Targeting SPP1 requires moving beyond ligand blockade

Liangzhan Sun
Zemin Zhang
Correspondence01 Jul 2026
Unifying the hallmarks of major depression through neuroimmune–metabolic–oxidative (NIMETOX) dysregulation: a mechanistic systems framework

Michael Maes
Abbas F. Almulla
Yingqiang Zhang
Review ArticleOpen Access13 Jul 2026
Macrophage CCRL2 promotes NLRP3 inflammasome activation to exacerbate atherosclerosis

Qian Cai
Zhen Duan
Rui He
Article13 Jul 2026
Fibroblast-derived CCL2 orchestrates immune responses and defends against Staphylococcus aureus skin infection

Tatsuya Dokoshi
Marta Palomo-Irigoyen
Richard L. Gallo
ArticleOpen Access22 Jun 2026
A cholinergic checkpoint controls autoantibody selection via somatic hypermutation in lupus germinal centers

Jin Li
Yimei Lai
Hui Zhang
Article22 Jun 2026
Sympathetic immunomodulation suppresses liver metastasis by maintaining the balance between norepinephrine concentration and the α2a/β2-AR ratio

Lulu Gao
Jian Li
Zhihong Zhang
Article23 Jun 2026

Volume 23 Issue 8

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Behind the Paper

Behind the Paper is a channel for researchers to share the real stories behind the latest research papers, from conception to publication, the highs and the lows. We welcome our authors to share the methods they used to conduct their studies, as well as experiences of collaborating with other teams and across disciplines.

Browse articles

Platelet-derived serotonin epigenetically programs macrophage alternative activation to orchestrate type 2 airway inflammation

Ru Tang
Guofang Xia
Feng Liu
ArticleOpen Access30 Jul 2026
Tumor cell-released autophagosome (TRAP) programs inflammatory CAFs to drive the immune-excluded TIME through C3a

Xuru Wang
Yiting Wei
Lixin Wang
Article29 Jul 2026
NLRC3 enhances antitumor immunity by specifically negatively regulating M-MDSCs in a STING-dependent manner

Yuling Fu
Xiaoxia Zhan
Shengfeng Hu
Article29 Jul 2026
The Parkinson’s disease-linked G2019S mutation of LRRK2 increases NADPH oxidase-2 activity in neutrophils for superior control of bacterial infections

Kate Hurley
Rachel Kaul
Subash Sad
Article17 Jul 2026
Unifying the hallmarks of major depression through neuroimmune–metabolic–oxidative (NIMETOX) dysregulation: a mechanistic systems framework

Michael Maes
Abbas F. Almulla
Yingqiang Zhang
Review ArticleOpen Access13 Jul 2026
Macrophage CCRL2 promotes NLRP3 inflammasome activation to exacerbate atherosclerosis

Qian Cai
Zhen Duan
Rui He
Article13 Jul 2026
Targeting SPP1 requires moving beyond ligand blockade

Liangzhan Sun
Zemin Zhang
Correspondence01 Jul 2026
FAM234A acts as a switch between Th17 and Treg cell fate decisions that control inflammatory bowel disease

Zhaoqi Zhang
Chenxu Zhao
Yong Zhao
Article01 Jul 2026
Itaconate induces noncanonical AIM2-dependent PANoptosis in sepsis

Hayeon Kim
SangJoon Lee
Comment25 Jun 2026

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