Type 2 Diabetes ADA-EASD Treatment Guidelines 2012
November 1, 2012 by Leave a Comment
On April 19, 2012, the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) released a new statement on the management of type 2 diabetes mellitus. These much-anticipated new treatment guidelines rely on a more individualised approach, and not as much on a strict glycated haemoglobin (HbA1c) target. The impetus […]
Type 2 diabetes – Table to guide treatment selection
November 1, 2012 by Leave a Comment
Table 1: Recommendations to guide treatment selection in combination therapy Favoured candidates now include the newer “incretin-based” therapies: DPP-4 inhibitors and GLP-1 RA are now as equal options with “established” therapies, some of which are cast in a more negative light (see below) DPP-4 inhibitors While still somewhat expensive, and modestly effective in HbA1c reduction, […]
Table 2 – Pros and cons of different type-2 diabetes options
November 1, 2012 by Leave a Comment
Table 2: Pros and cons of antiglycaemic therapy in type 2 diabetes Active ingredient Pros Cons Insulin sensitisers Biguanides metformin Extensive experience No weight gain No hypoglycaemia Likely ↓ CVD events (UKPDS) Low cost GI side-effects (diarrhoea, abdominal cramping) Lactic acidosis risk (rare) Vitamin B12 deficiency Multiple contraindications: CKD, acidosis, hypoxia, dehydration, etc. Thiazolidinedione pioglitazone […]
Type 2 Diabetes ADA-EASD Treatment Guidelines 2012 – Algorithms
November 1, 2012 by Leave a Comment
Download PDF: Algorithm – Diabetes general recommendations 2012 Algorithm – Adapted recommendations 2012 to avoid hypoglycaemia Algorithm – Diabetes adapted recommendations 2012 to avoid weight gain
Jentadueto approved for Type 2 Diabetes
November 1, 2012 by Leave a Comment
Boehringer Ingelheim Ltd and Eli Lilly & Co Ltd wish to announce that Jentadueto, a single tablet combination of the DPP-4 inhibitor linagliptin (the active ingredient in Trajenta tablets) and metformin, has been approved by the European Commission. Jentadueto provides a new, single-tablet treatment option, taken twice-daily, for adults with type 2 diabetes who need […]
Adcirca
November 1, 2012 by Leave a Comment
Company: Eli Lilly & Co. (Ireland) Ltd. Legal category: Prescription. High Tech. Sport permitted. Active ingredient: Tadalafil 20mg. Description: Orange, almond-shaped film-coated tablets marked 4467 on one side. Presentation: 56, €518. Indications: Treatment of pulmonary arterial hypertension, classified as WHO functional class II and III, to improve exercise capacity. Pharmacology: Tadalafil is a potent and […]
Bonasol Once Weekly
November 1, 2012 by Leave a Comment
Company: Fannin Ltd. Legal category: Prescription. GMS. Sport permitted. Active ingredient: Alendronic acid (as Na+ alendronate trihydrate) 70mg/100ml. Description: Orange-coloured solution. Presentation: 100ml-4, €19.83. Indications: Treatment of postmenopausal osteoporosis. Reduces risk of vertebral and hip fractures. Pharmacology: Alendronic acid is a bisphosphonate that inhibits osteoclastic bone resorption with no direct effect on bone formation. Activity […]
Bonefurbit
November 1, 2012 by Leave a Comment
Company: Rowex Ltd. Legal category: Prescription. GMS. Sport permitted. Active ingredient: Ibandronic acid 150mg. Description: White, oblong film-coated tablet marked LC on one side. Presentation: 1, €19.64. Indications: Treatment of osteoporosis in postmenopausal women at increased risk of fractures. Demonstrated efficacy on vertebral fractures; efficacy on femoral neck fractures not established. Pharmacology: Ibandronic acid is […]
Dancex
November 1, 2012 by Leave a Comment
Company: Rowex Ltd. Legal category: Prescription. GMS. Sport prohibited in competition. Active ingredient: Oxycodone HCl 5mg, 10mg, 20mg. Description: Blue, white or pink round, biconvex prolonged-release tablets respectively. Presentation: 5mg-28, €11.87; 10mg-56, €19.15; 20mg-56, €38.30. Indication: Severe pain which can be adequately managed only with opioid analgesics. Pharmacology: Oxycodone shows an affinity for kappa, mu […]
Loading ...
